Internet-based Links for Finding "Evidence"

The links below are extracted from the PowerPoint presentation on "Evidence-based Medicine" given in the KCOM Differential Diagnosis in July 1999 by Robert W. Baer, Ph.D.  The links include general starting points of various sources of "Evidence" available on the Internet.  Some specific examples are given with respect to "sample seaches" on "evidence related to cardiac enzymes".  The links and samples are NOT exhaustive.  More exhaustive EBM resource listings include: the Randolph and Markovitz Site and the IntensiveCare.com site, especially the tutorial.

The original presentation and the slides containing the original "hot" hyperlinks are also available (at least to Windows users with Internet Explorer) on this site.  This page is provided mainly as an alternative for those with older Macintosh computers, older viewing software,  and Netscape browsers, (or anyone else who has found the original formats inaccessible or inconvenient).

General Internet

National Library of Medicine

PubMed Samples (Sample cardiac enzyme articles)

1. (Abstract) Prospective, double blind: Troponin-I, CK-MB, Unselected patients
2. (Abstract) Small Trial (Serial Enzymes 0, 3, 6 hr.): Mixed patient pool, sensitivity and specificity

Internet Grateful Med Samples
    Home Page <go>
    Cardiac Enzyme Articles (Cardiac Enzymes AND Myocardial Infarction)
       1.   Serial CK-MB monoclonal Clinical Trial (ppv & npv at 0, 3 hr. n=1042) Young, GP, Acad Emerg Med 1997 Sep;4(9):869-77 <go>
        2.  c7E3 Fab Antiplatelet Therapy in Unstable Refractory Angina (CAPTURE) & Troponin T) (NEJM)

Evidence-based Medicine Journals

Journal of Family Practice

1. Evidence-based focus (home)
2. Patient-Oriented Evidence that Matters (POEMS)(home)(index)
3. Cardiac Enzymes: Troponin-I POEM (annotation)
4. Cardiac Enzymes: Troponin-T POEM (annotation)

ACP Journal Club (Structured Abstracts of Evidence)

1. Current Issue (contents)
2. D-Dimer Assay diagnoses PE (Sample)

Evidence-based Medicine (Structured Abstracts of Evidence)

1. Contents (July / Aug 1999)
2. Example EBM (Cardiac Enzyme Evidence): Abstracted: November/December 1998 issue

Physician-Oriented Commercial Sites

Cyberounds (free subscription required)

1. Cyberounds Example: Cardiac Enzymes
2. Cyberounds Example: Stress Testing

Medscape (free subscription required)

1. General Practice Home
2. Internal Medicine Home
3. Women’s Health Home
4. Pediatrics Home
5. Surgery Home
6. Medscape: Cardiac Enzymes (Post-stent) - (reprinted from Am. Heart J.)

Databases of Evidence and Clinical Trials

DARE Database (York) and other NCR Databases

1. Database of Abstracts of Reviews of Effectiveness (DARE)
2. NHS Economic Evaluation Database (search)
3. Health Technology Assessment Database (HTA) (search)

Cochrane Database (meta-analysis)

1. Abstract search (home)
2. Review Groups (main list) (heart group)
3. Subject guide (list)
4. Internet access (abstracts)
5. Examples: Deep vein thrombosis & heparin (abstract)
6. Cochrane library (fee-based) (home)

Disease-oriented Organizations

American Heart Association

1. (Home)
2. AHA Recommendation: Cardiac enzymes
3. Search
4. Statistics
5. New diagnostic techniques Sessions (Contrast Echo, MRI Movie)

American Cancer Society (Home)

National Diabetes Association (Home)

Center for Disease Control (CDC)

1. Health Statistics (home)
2. Data Warehouse page (URL)

Clinical Practice Guidelines (U.S. Government)

1. National Guideline Clearinghouse (frames)(no frames)
2. Agency for Health Care Policy and Research (home)
3. Evidence-based practice centers (home)

Medical School & Academic Sites

Virtual Hospital (home)

1. Healthcare professionals (index)
2. Multimedia Textbooks (index)
3. Clinical Guidelines (index)

MedicalStudent.com   Digital Library (index)

Other Sites of Interest for Evidence-base Medicine

Links to over 300 statistical calculators (index)

More Evidence-Based Medicine links (extensive list) (home)

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